Neurodegenerative Diseases Discussion

2. What are the underlying molecular mechanisms responsible for the development and progression of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, and how can this knowledge be leveraged to design novel therapeutic interventions?

– What are the key genetic and environmental factors contributing to the onset and progression of neurodegenerative diseases, and how do they influence the aggregation and accumulation of misfolded proteins, such as beta-amyloid and alpha-synuclein?

– How do neuroinflammatory processes and the dysregulation of cellular processes, such as autophagy and proteostasis, contribute to the pathogenesis of neurodegenerative disorders, and what potential therapeutic targets can be identified within these pathways?