Answer and fill in the question in the template document
Life Sciences Workbook
To accompany RPL portfolio for
Pg. Dip/MSc nursing programme.
Candidate Name
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Candidate Course
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Date of completion
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1
Contents
Life Sciences Workbook ………………………………………………………. 1
The Body Compartments, Cells and Homeostasis …………………… 4
The Skin (Integumentary System), Wound Healing and
Temperature Regulation ………………………………………………………. 8
The Musculo Skeletal System …………………………………………….. 13
The Heart ………………………………………………………………………… 18
The Blood and Blood Vessels …………………………………………….. 21
The Respiratory System …………………………………………………….. 25
The Renal System, Fluid and Electrolytes …………………………….. 29
The Gastro Intestinal System ……………………………………………… 34
The Nervous System …………………………………………………………. 38
The Endocrine System ………………………………………………………. 41
The Reproductive System ………………………………………………….. 43
Learning Resources ………………………………………………………….. 45
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Workbook on Body Systems
The aim of this workbook is to enable our Pg Dip / MSc nursing
applicants, who have been offered a place on the programme and
who have not studied a health/science related degree before, to
develop and enhance their knowledge of the structures and
systems of the body.
It is essential to have a good understanding of the anatomy and
physiology of the body prior to commencing your programme of
study as one of your modules will build upon this knowledge.
The completed workbook must be submitted with your RPL
portfolio as evidence that you have acquired this knowledge.
You may use any resources you wish to help you with its
completion and at the back of this workbook you will find a
recommended reading list.
3
The Body Compartments, Cells and
Homeostasis
1) Define the following terms:Cell
Cell is the smallest unit of life
Organ
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System
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Body compartments
2) Identify the location of the following organs in the body
cavities:
Spinal
cord
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Lungs
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Kidneys
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Heart
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Liver
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Stomach
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4
Cells
3) Insert the appropriate words in the blank spaces against
the correct description below:Ribosomes
Mitochondria
Nucleus
Golgi apparatus
Centrioles
mitochondria
is where production of energy in the form of
ATP occurs
Centrioles
are found near the nucleus and are
involved in cell division
Ribosomes
is an intracellular factory that manufactures
protein
Golgi Apparatus
is the processing and packaging station for
the protein from the endoplasmic reticulum.
Nucleus
is essential for all cellular activities and
contains genetic materials
4)
Insert the following appropriate words in the blank
space against the correct description below:-
Osmosis
Active transport
Pinocytosis
Simple diffusion
Lysosomes
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text.
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text.
is the movement of water through a semi
permeable membrane from a region of low
solute
is the movement of solutes/gas through a
semi permeable membrane from a region
of higher solute/gas
5
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text.
Click or tap here to enter
text.
Click or tap here to enter
text.
is a mechanism by which cell membrane
indents and actually engulf the substance
to be absorbed into the cell
requires energy derived from cellular
chemical reactions to move molecules or
ions against their concentration gradient
contains digestive enzymes which digest
bacteria and cellular debris
5) Which word fully describes the cell structure; please enter
your response in the spaces provided under each heading?
Cell structure
Location
Function
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enter text.
Forms the external
boundary of cells
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enter text.
Found in the
cytoplasm
Serves as a selectively
permeable membrane
which regulate material to
and from the cell
Contains digestive
enzymes
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enter text.
Scattered
throughout the cells
Control release of energy
from food and forms ATP
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enter text.
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enter text.
Found in all cells
Manufactures protein
Found in the
cytoplasm
Contains ribosomes and
is involved in protein
synthesis
6) Describe the structure of the cell membrane
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7) Explain the function of the cell membrane
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8) Explain briefly what occurs during osmosis
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9) Explain how diffusion across the cell membrane occurs
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Homeostasis
10)
What are ‘receptors’?
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11) What are the receptors that detect body temperature
called?
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12) The ‘pathway’ that conveys messages towards the control
centre is known as the Click or tap here to enter text.
pathway.
13) The ‘pathway’ that conveys messages away from the
control centre is known as the Click or tap here to enter text.
pathway.
14) What are ‘effectors’?
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.
15) The 2 most important systems involved in regulation and
the maintenance of homeostasis are:
1
2
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Click or tap here to enter text.
16) Explain how the body strives to maintain homeostasis.
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7
The Skin (Integumentary System), Wound
Healing and Temperature Regulation
The Skin
1) Select the correct term with the definition given.
Stratum basale
Hypodermis
Stratum corneum
Papillary layer
Stratum granulosum
Epidermis (whole)
Stratum lucidum
Dermis (whole)
Term
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Description
Layer of cells present only in thick skin
Layer containing all dead cells
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Layer that sloughs off
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Contains the blood vessels
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Epidermal layer undergoing mitosis (cell
division)
Cells with most keratin in them
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Outer layer of skin
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Deeper layer of skin
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Layer where accessory structures are
found
Epidermal layer where most melanocytes
are found
Layer that produces lipid rich secretion
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Epidermal layer containing the oldest cells
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Largely adipose tissue and anchors skin
to underlying tissue
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2) Name the 5 layers of the epidermis starting with the
innermost layer
1
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2
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3
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4
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5
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3) For the protective functions of skin, match the term
given with the definition of the role each part plays in
providing protection. Choose an answer from the
following:
Melanin, Sweat, Normal flora, Skin, Macrophages,
Lipids, Langerhans cells, Keratin
Answer
Click or tap
here to enter
text.
Click or tap
here to enter
text.
Click or tap
here to enter
text.
Click or tap
here to enter
text.
Description
Involved in the sensation of touch
Resist invasion by organisms by preventing harmful
bacteria from colonising
Prevent some evaporation on skin, protects hair and
skin from drying out, antibacterial due to low pH
Protects from UV light
9
Click or tap
Increases heat loss
here to enter
text.
Click or tap
Forms a protective barrier and protects underlying
here to enter tissues
text.
Click or tap
Phagocytose bacteria and viruses
here to enter
text.
Click or tap
A tough fibrous protein
here to enter
text.
4) What is an exocrine gland?
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5) List some of the structures found in the dermis
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6) List the cells found in the epidermis and briefly describe
their function
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Wound healing
7) If the epidermis is damaged during injury, which layer of
the epidermis enables new cells to grow?
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8) Name the cells found in the skin that protect the skin from
pathogenic organisms
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9) State what happens during each stage of wound healing.
Inflammation
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Regeneration
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Maturation
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Homeostatic control of temperature
10) Using the key choices, select the terms that match the
following descriptions pertaining to body temperature
regulation.
Key choices
Hypothermia, Hyperthermia, Heat, Sensory (afferent pathway),
Thermoreceptors, Blood, Hypothalamus, Sweating, Shivering,
Temperature control centre, Motor (efferent pathway),
Vasoconstriction, Vasodilation
Answer
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enter text.
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enter text.
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enter text.
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enter text.
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enter text.
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enter text.
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enter text.
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enter text.
Description
Produced as a result of cell metabolism
Thermoregulatory centre
Medium that distributes heat to all the tissues
and carries it to the skin
Site of the body’s temperature control centre
Nerves that carry information about
temperature to the hypothalamus (control
centre)
Nerves convey impulses away from the control
centre and activate the effectors
Means of liberating excess body heat
Extremely low body temperature
11
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enter text.
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enter text.
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enter text.
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enter text.
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enter text.
Extremely high body temperature
Receptors that detect temperature
Generates heat when temperature falls too low
Increases blood flow to the skin
Reduces blood flow to the skin
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The Musculo Skeletal System
1) How many bones does the adult human body have?
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2) Name 3 substances that bone contains when fully
developed
1
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2
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3
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3) Name, and give examples of the four main types (shapes)
of bone
1
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2
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3
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4
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4) State the main function of a:
i) ligament
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ii) tendon
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5) List the main functions of the skeleton
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6) What are the two types of bone tissue?
1
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2
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7) What are the functions of:
i)
Osteoblasts
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ii)
Osteoclasts
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8) Name the 5 main regions of the vertebral column and state
how many vertebrae there are in each region
1
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2
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3
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4
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5
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14
Joints, Tendons and Ligaments
9) Name the three types of joint
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10) Give two examples of where in the body each of the
three types of joint can be found
1
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2
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3
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11)
What type of joint allows most movement?
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12)
What type of joint does not allow movement?
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13)
What attaches muscle to bone?
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14)
Outline the function(s) of ‘tendons’
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15)
Outline the function(s) of ‘ligaments’
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15
Muscles
16) Complete the following table, identifying the type of
muscle
Type of muscle
Click or tap here to
enter text.
Click or tap here to
enter text.
Click or tap here to
enter text.
Click or tap here to
enter text.
Click or tap here to
enter text.
Click or tap here to
enter text.
Click or tap here to
enter text.
Description
Is under the control of the will (voluntary)
Moves substances such as food through the
gastrointestinal tract
Enables movement and ability to hold the
body upright
Is activated by a specialised conducting
system in the heart
Causes blood vessels to constrict
Has short branching fibres
2 types of muscle not under the control of
the will (involuntary)
17) The 3 types of muscle tissues exhibit certain similarities
and differences. Tick the appropriate one in the following
table to indicate the specific characteristic of each muscle
type
Voluntary controlled
Involuntary
Controlled
Single nucleus in
each cell
Found attached to
bone
Allows the
movement of your
eyeball
Found in walls of
stomach uterus and
arteries
Skeletal
☐
Cardiac
☐
Smooth
☐
☐
☐
☐
☐
☐
☐
☐
☐
☐
☐
☐
☐
☐
☐
☐
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Contain cylindrical
cells with branching
end
Concerned with
locomotion of the
body
☐
☐
☐
☐
☐
☐
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The Heart
1) The site in the thoracic cavity that the heart occupies is
called Click or tap here to enter text.
2) The structure that separates the right side of the heart from
the left side is called the Click or tap here to enter text.
3) Oxygenated blood found is found on which side of the
heart?
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4) Name the tiny muscle that anchors the chordae tendinae to
the inner wall of the heart.
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5) What are Chordae Tendinae and what are their functions?
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6) Explain the reason why the atria has thinner muscle
compared to that of the ventricles
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7) Describe the function of the conducting system in the
heart.
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8) Explain why one chamber of the heart has a much thicker
muscle wall compared to other chambers and give a
reason for this difference.
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9) Describe the flow of blood through the heart starting from
the right atrium, ending with the left ventricle. (Name the
chambers, valves and blood vessels that enter and leave
each chamber).
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10) Name the 3 layers of the heart and explain each of their
functions
1
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2
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3
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11) Describe pulmonary circulation; where does it start and
where does it finish (name the blood vessels, heart
chambers and heart valves)?
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12) Name the blood vessel(s) that carry blood away from the
left ventricle
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13) Name the blood vessel(s) that carry blood away from the
right ventricle
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14) Name the blood vessel(s) that carry blood into the left
atrium
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15) Name the blood vessel(s) that carry blood into the right
atrium.
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16) Name the parts of the conducting system numbered 1-5
on the diagram below
1
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2
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3
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4
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5
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The Blood and Blood Vessels
1) Match the description with the relevant term below:Tunica externa
Tunica media
Tunica intima
Term
Description
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single thin layer of endothelium
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bulky middle coat, containing
smooth muscle and elastin
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anchors blood vessels to
surrounding structures
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the innermost layer
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also called the adventitia
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which is in contact with blood in the
lumen
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a supporting and protecting coat
2)Define the term ‘vein’
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3)Define the term ’artery’
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4)Define the term ‘ capillary’
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5) Artery walls have three layers; name these layers
1
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2
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3
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6) Vein walls have three layers; name these layers
1
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2
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3
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7) Insert the appropriate words/letter against the description
below:Cardiac output, Blood pressure, Korotkoff sounds, pressure
points, diastolic blood pressure, Systolic blood pressure,
pulse
Term
Description
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an expansion and recoil of an artery
following a heart beat
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pressure exerted by blood against
the blood vessel wall.
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maximum blood pressure following
left ventricular contraction
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minimum blood pressure following
cardiac relaxation.
22
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point at body surfaces where a
pulse may be felt
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the sounds heard over an artery
when blood pressure is determined
by the auscultation.
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one of the factors contributing to the
maintenance of blood pressure.
8) List the characteristics of blood
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9) Name the two main components in whole blood and the
percentage of each one
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10) List the functions of a red blood cell.
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11) What is the blood volume of an average size adult?
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12) List the main blood groups.
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13) Which cells are more numerous in the blood?
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14) What is/are the general function(s) of white blood cells?
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15) What is/are the general function(s) of red blood cells?
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16) Describe the formation, structure, shape and life span of a
red blood cell
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24
The Respiratory System
1) In the correct order, list the structures that air passes
through before it reaches the lungs.
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2) List the structures that help to change the characteristic of
inspired air before it reaches the lungs.
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3) Explain the changes that occur to the characteristics of
inspired air before it enters the lungs
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4) List the structures that air passes through as it passes
from the trachea to the alveoli
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5) Where are the cilia found in the respiratory tract?
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6) Explain the functions of the:
Cillia
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Goblet
cells
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Mucus
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7) What is an alveolus?
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8) What is the ‘respiratory membrane’?
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9) How many cells thick are capillary walls?
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10)
What type of cells form the walls of the capillary?
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11)
What type of cells form the walls of the alveolus?
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12)
How many cells thick are alveoli walls?
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13)
Explain the changes that occur to the chest cavity
during
Inspiration Click or tap here to enter text.
Expiration Click or tap here to enter text.
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14) Explain the mechanism which causes air to move in and
out of the lungs (chest movement)
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15) Describe the location and functions of the pleural
membrane.
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16)
What is the function of pulmonary fluid?
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17) Name the layers of the pleural membrane and state
where each layer is situated
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18) Explain how the pleural membrane enables the lungs to
expand as the thoracic cavity expands
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19) Explain how gases move across the respiratory
membrane
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20) Explain how oxygen is transported in the blood stream
(give percentages)
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21) Explain the thee ways by which carbon dioxide is
transported in the blood stream (give percentages)
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22)
Describe diffusion
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23) Explain why diffusion is important for the movement of
gases
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The Renal System, Fluid and Electrolytes
1) Label the diagram below.
A
B
C
D
E
F
A
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B
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C
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D
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E
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F
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2) List the functions of the renal system
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3) List the three processes by which urine is formed
1
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2
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3
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4) Describe what occurs during each of the three process of
urine formation
1
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2
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3
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5) List the contents of urine
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6) List the parts of a nephron
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7) What helps urine flow down the ureters?
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8) Name the blood vessels that take blood to and away from
the glomerulus
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9) What is the function of the bladder?
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10) List the structures urine flows through after it leaves the
collecting duct until it leaves the body
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11) Describe six different functions of the kidney
1
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2
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3
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4
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5
Click or tap here to enter text.
6
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Fluid Balance
1) State the 3 ways by which we acquire water
1
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2
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3
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2) How much should the average sized adult drink per day?
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3) How much water do we lose per day?
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4) State the 3 main ways fluid body fluid is lost (in health) and
state how much is lost by each way
1
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2
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3
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5) Explain what electrolytes are
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6) What are the 2 fluid compartments of the body?
1
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2
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7) Explain where each fluid compartment is located
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8) What is a cation?
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9) What is an anion?
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10)
List some of the cations and anions found in the body
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11) Which ion is involved in maintaining the ‘acid balance’
(pH)?
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12)
What is the normal pH of blood?
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33
The Gastro Intestinal System
1) What is an enzyme?
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2) Name the enzyme in saliva that starts the breakdown of
carbohydrates.
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3) Name the salivary glands and list their position in the
mouth
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4) Name the constituents of saliva.
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5) Define a sphincter
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6) The Sphincter found between the stomach and the small
intestine is called:
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7) Name the numbered structures in the diagram below:
1
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2
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3
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4
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5
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6
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7
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8) What type of muscle contraction enables the movement of
food through the digestive tract?
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9) Describe the following :The length of the
small intestine
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The different
sections of the
small intestine
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The functions of
the small
intestine.
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10)
Describe the following: –
The length,
position and
different parts of
the large intestine
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The functions of
the large intestine
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11) Explain the chemical digestion of the following
foodstuffs. Name the enzymes, where they are released
from and how they break down each of the following:
(i)
Protein
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(i)
Fats
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(iii) Carbohydrates
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13) Before each nutrient can be absorbed it is broken down
into its smallest component. What are the following
absorbed as:
Nutrient
Absorbed as:
Protein
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Fats
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Carbohydrates Click or tap here to enter text.
14)
Define the following terms :-
Ingestion
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Digestion
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Absorption
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Excretion
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15) Explain the processes that occur during the act of
defecation.
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The Nervous System
1) Draw and label a typical neurone
2) Name the 2 parts that form the central nervous system?
1
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2
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3) What are the functions of dendrites?
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4) What are the functions of axons?
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5) Explain the function(s) of sensory neurones
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6) Explain the function(s) of motor neurones
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7) What is a synapse?
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8) What are neuro transmitters? Where are they released?
What are their functions?
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9) Name the two branches of the autonomic nervous system.
1
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2
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10) What are the coverings of the brain and spinal cord
collectively known as.?
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11)
What does CSF stand for and where is it produced?
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12)
List the functions of CSF.
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13)
The outer part of the brain is the Click or tap here to enter
text.
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This is subdivided into 4 different lobes. These lobes have
the same names as the portion of the skull that covers that
lobe. The 4 different lobes are called:
1
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2
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3
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4
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14)
The functions of each lobe are:
1
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2
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3
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4
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15)
What is the function of the nervous system?
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16) Describe the functional effects of the sympathetic
nervous system
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17) Describe the functional effects of the parasympathetic
nervous system
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The Endocrine System
1) Explain the difference between an endocrine and an
exocrine gland.
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2) Give examples of some exocrine and endocrine glands.
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3) What is a hormone?
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4) Explain why hormones only influence specific cells and
tissues of the body.
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5) Fill in the names of the hormones produced by the
following endocrine glands and briefly outline their action
Gland
Posterior
Pituitary
Anterior
Pituitary
Hormone
1
Name and Action
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2
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1
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2
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3
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4
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5
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6
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1
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2
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3
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Parathyroid 1
Glands
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2
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1
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2
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1
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2
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1
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2
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The
Thyroid
Gland
Adrenal
Medulla
Adrenal
Cortex
Pancreas
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The Reproductive System
1) Name the hormones released by the anterior pituitary that
act on the ovaries
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2) On which day of the menstrual cycle is the mature egg
(ovum) released?
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3) Into what area is the ovulated cell released?
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4) Describe the structure and explain the function of Fimbriae
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5) List the three layers of the uterus, starting with the outer
layer.
1
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2
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3
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6) Explain how the ovum moves along the fallopian tube
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7) Where does fertilization usually take place?
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8) On what days of the menstrual cycle can fertilisation
occur? Explain why it can only occur on these days.
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9) Which part of the uterus is broken down and lost during
menstruation?
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10) Name the organ that delivers semen to the female
reproductive tract
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11)
Name the site of sperm and testosterone production
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12)
Name the external sac that houses the testes
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13) Name the gland that surrounds the urethra at the base of
the bladder and produces a milky fluid
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14) Approximately how much fluid is released per
ejaculation?
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15) Approximately how many sperm are there in each 1ml of
ejaculatory fluid?
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Learning Resources
Marieb, E.N. (2010) Essentials of Human Anatomy and
Physiology (10th Ed) Pearson, Benjamin Cummings San
Francisco.
McKissock, C. (2014) Great Ways to Learn Anatomy and
Physiology (2nd ed). Palgrave. London.
Tortora, G. & Derrickson, B. (2013) Essentials of Anatomy
and Physiology (9th Ed) John Wiley and sons, (Asia)
Thibodeau, G., Patton, K. (2013) The Human Body in Health
and Disease. (6th Ed) Mosby, Inc. USA.
Marieb, E.N., Hoehn, K. (2014) Human Anatomy and
Physiology (9th Ed) Pearson, Benjamin Cummings San
Francisco.
Tortora G.J., Derrickson B (2012) Principles of Anatomy and
Physiology: Organisation, Support and Movement and
Control Systems of the Human Body (13th Ed) John Wiley
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