Gentamicin Antibiotics Paper

1. This is an independent research paper on an antibiotic selected by you or with assistance from the professor. Your topic must be approved by the professor. This assignment is must be done for 5 pages . The paper should include:

1. An introduction to the discovery of the drug
2. The mechanism of action
3. The synthesis of the drug
4. The clinical applications and indications
5. Discussion of resistance issues.Begin developing ideas for a final paper topic.

Major Assignment 1 – Paper Grading Rubric
(THIS RUBRIC WILL GIVE A % GRADE ON THE ASSIGNMENT
WHICH WILL BE INCOORPERATED INTO YOUR COURSE GRADE
AS A % OF THE 250 COURSE POINTS ALLOCATED TO THIS
ASSIGNMENT)
Name:
Course: CHEM05530
CATEGORY
Unacceptable
(Below Standards)
Acceptable
(Meets Standards)
Good
(Occasionally Exceeds)
Excellent
(Exceeds Standards)
Introduction /
Background /
Discovery
Does not
adequately convey
topic. Does not
describe subtopics
to be reviewed. (0
points)
Conveys topic, but
not key
question(s).
Describes
subtopics to be
reviewed. ( 1 0
points)
Conveys topic and
key question(s).
Clearly delineates
subtopics to be
reviewed. ( 2 0
points)
Confusing or
absent description
of synthetic
routes.
Inadequate
outline of
purification
techniques. (0
points)
Superficial
description of
synthetic routes
and purification
techniques. (20
points)
Description of
synthetic routes.
Outline of
purification
techniques. (30
points)
Strong
introduction of
topic’s key
question(s), terms.
Clearly delineates
subtopics to be
reviewed. ( 3 0
points)
Clear description of
synthetic routes.
Thorough, systematic
outline of purification
techniques. (40
points)
Unclear,
incomplete or
absent descriptions
of how the drug
works and how
resistance
develops. (0
points)
General
descriptions of how
the drug works and
how resistance
develops. (40
points)
Mechanistic
descriptions of how the
drug works and how
resistance develops.
(60 points)
Clear, detailed,
mechanistic
descriptions of how
the drug works and
how resistance
develops. (80
points)
80 points
The application of
the compound is
discussed but is
unclear and
incomplete. (0
points)
Review of key
applications.
Some discussion
of impact of the
application of the
compound. (20
points)
Good review of key
applications.
Discussion of impact
of the application of
the compound. (30
points)
Strong review of
key applications.
Insightful
discussion of
impact of the
application of the
compound. (40
points)
40 points
A significant
number of
aspects missing.
(0 points)
A few aspects of
market analysis are
missing; unclear
outlook. (20
points)
A few aspects of
market analysis are
missing, but does not
detract from overall
message. (30 points)
40 points
Few sources
supporting thesis.
Sources
insignificant or
unsubstantiated.
Incorrect format
(0 points)
Sources generally
acceptable but not
peer-reviewed
research
(evidence) based.
Some errors in
format (10 points)
Sources well selected
to support thesis with
some research in
support of thesis.
Mostly correct format
(15 points)
The paper is
completely
outlines current
and future market
prospects. (40
points)
Strong peerreviewed research
based support for
thesis. Correct
format. (20
points)
Synthesis
&
Purification
Mechanism of
Action / Resistance
Applications
Market
Analysis
Citations &
References
Comments:
Total Points:
SCORE
30 points
40 points
20 points