write an article on using of rtms and antidepressant drugs simultaneously to increase the therapeutic efficacy for patients with psychotic depression

Hi, I am looking for someone to write an article on using of rtms and antidepressant drugs simultaneously to increase the therapeutic efficacy for patients with psychotic depression Paper must be at least 1000 words. Please, no plagiarized work!

Psychotic depression is a fairly common psychiatric condition that has been found to occur in nearly 20% of patients with major depression (Flores et al., 2006). The preferred treatment for psychotic depression so far has consisted of tricyclic antidepressants (TCAs) as also neuroleptic and electroconvulsive therapies (O’Neal et al., 2000). Patients with psychotic depression have a more severely disordered hypothalamic-pituitary-adrenocortical (HPA) axis (Kathol et al., 1989). The psychotic features of psychotic depression have been attributed also to excessive glucocorticoid activity (Schatzberg et al., 1985). Interestingly, HPA axis activity is, to a large extent, regulated by the combination of mineralocorticoid receptors (MR) and glucocorticoid receptors (GR) (Spencer et al.

Don't use plagiarized sources. Get Your Custom Essay on
write an article on using of rtms and antidepressant drugs simultaneously to increase the therapeutic efficacy for patients with psychotic depression
Just from $13/Page
Order Essay

, 1998. Young et al., 2003). Any mismatch between them could lead to inappropriate responses to stress, and incidence of major depression (Young et al., 2003). Decreases in MR sensitivity postulated to occur in major depression could result in elevated cortisol levels (Gesing et al., 2001. Young et al., 2003). In contrast, GR gives rise to feedback modifications in response to rising levels of cortisol as, for example, in response to stress or following the circadian rhythm. Hence, a GR antagonist e.g., the anti-progesterone steroid mifepristone (dimethylaminophenyl (17(-hydroxy-11(1(4-dimethylaminophenyl) 17(1- propynyl)estra-4,9-dien-3-one) exerts a powerful effect in the rising section of the HPA axis (Flores et al., 2006). A major effect of mifepristone occurs through obstruction of GR in crucial regions of the brain and in monaminergic nuclei, thereby, directly leading to recovery of symptomatic and cognitive faculties.

First observed by Bickford et al.

Calculate your order
Pages (275 words)
Standard price: $0.00
Client Reviews
4.9
Sitejabber
4.6
Trustpilot
4.8
Our Guarantees
100% Confidentiality
Information about customers is confidential and never disclosed to third parties.
Original Writing
We complete all papers from scratch. You can get a plagiarism report.
Timely Delivery
No missed deadlines – 97% of assignments are completed in time.
Money Back
If you're confident that a writer didn't follow your order details, ask for a refund.

Calculate the price of your order

You will get a personal manager and a discount.
We'll send you the first draft for approval by at
Total price:
$0.00
Power up Your Academic Success with the
Team of Professionals. We’ve Got Your Back.
Power up Your Study Success with Experts We’ve Got Your Back.
error: Content is protected !!
Live Chat+1(978) 822-0999EmailWhatsApp

Order your essay today and save 20% with the discount code GOODESSAY